Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Glycogene class |
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Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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H2O | + |
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→ |
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+ |
|
• Hydrolyzes galactosylceramide on glycolipids.
• Deficiency of this enzyme activity results in Krabbe disease.
ER | Cis- | Medial- | Trans- | TGN |
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GALC/hsa-miR-7109-3p |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
---|---|---|---|---|---|---|---|---|
5'...UUGGAACAGUAUAU
GAGGCUU
U...
3' GACCUUCCCGUCCU CUCCGAA C |
7mer-m8 | 94-100 | -0.293 | 97.0 | -0.293 | 98.0 | noncon | |
5'...UAAGAGUCUAACAU
AGGCUUA
G...
3' GACCUUCCCGUCCUC UCCGAA C |
7mer-A1 | 1141-1147 | -0.073 | 73.0 | -0.073 | 82.0 | noncon |