GlyClass

GlycoEnzDB
Comprehensive glycoEnzyme database and dynamic pathway generation

Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).

GlycoEnzDB
Create glycosylation pathway
Custom database generation
Instructions/Reference
 
Pathway Map
C1GALT1C1



General Information
Gene Symbol:   
C1GALT1C1
Protein name:   
C1GALT1-specific chaperone 1
Enzyme Class:   
CAZy Family:   
GT31
E.C. No:   
Organs:   
Reaction (SNFG):   

No reaction →
Reaction (IUBMB):   
No specified reaction.
About

Related Pathway
KEGG ORTHOLOGY:   
KEGG Pathway:   
No Record 
Reactome:   
R-HSA-5083632
Related Database
Organism:   
Homo sapiens
Uniprot:   
Q96EU7 
NCBI GeneID:   
29071
GlyMap GeneID:   
29071
DNA aRefSeq:   
NM_001011551.2 
Protein RefSeq:   
NP_001011551.1 
BRENDA:   
Kinetic info.
OMIM number:   
300611
GeneCards database:   
C1GALT1C1
Enzyme Specificity
Glycan Type:  
     O-linked (mucin type)
Compartment:  
     
Substrate:  
     No reaction
Product:  
     
Simulation Parameters
Mechaelis-Menten parameters (suggested)
VM:       (pmol/cell • hr)       KM:       (pM)
Relative conc of enzymes in compartment.(sum will be normalized to 1)
ER Cis- Medial- Trans- TGN










Expression Data in Tissue {ref. 5} Source from NCBI gene database
No expression data available.
Expression Data in Cells {ref. 13} Source from Cancer Cell Line Encyclopedia database
Kidney Lung Breast Prostate Large intestine Ovary HL60 haematopoietic and lymphoid tissue Skin Central nervous system 786O A498 ACHN CAKI1 UO31 A549 EKVX HOP62 HOP92 NCIH226 NCIH23 NCIH322 NCIH460 NCIH522 SHP77 BT549 HS578T MCF7 MDAMB231 MDAMB468 T47D DU145 PC3 HCT116 HCT15 HT29 KM12 SW620 OVCAR4 OVCAR8 IGROV1 SKOV3 HL60 K562 RPMI8226 LOXIMVI MALME3M RPMI7951 SKMEL28 SKMEL5 UACC257 UACC62 SF268 SF295 SF539 SNB75 140 120 100 80 60 40 20 0 Transcripts per million (TPM)
Transcription factor {ref. 10}
No high degree of confidence data
miRNA-GlycoEnzyme Interactome {ref. 9}
miRNA Name Pos. Context Score Frac. Wt. Context Frac. Conserved Quality
hsa-miR-6805-5p 1648-1655 -0.637 99.0 -0.032 45.0 noncon
hsa-miR-4758-3p 300-307 -0.616 99.0 -0.186 91.0 noncon
hsa-miR-4791 71-78 -0.612 99.0 -0.612 99.0 noncon
hsa-miR-4278 1649-1656 -0.569 98.0 -0.029 39.0 noncon
hsa-miR-633 246-253 -0.56 99.0 -0.486 99.0 noncon
hsa-miR-1206 187-194 -0.536 99.0 -0.467 99.0 noncon
hsa-miR-3201 71-78 -0.528 99.0 -0.528 99.0 noncon
hsa-miR-1266-5p 538-545 -0.528 99.0 -0.027 69.0 noncon
hsa-miR-7852-3p 67-74 -0.526 99.0 -0.526 99.0 noncon
hsa-miR-455-5p 304-311 -0.501 99.0 -0.155 89.0 noncon
hsa-miR-1468-3p 233-240 -0.469 99.0 -0.409 99.0 noncon
hsa-miR-4518 538-545 -0.455 99.0 -0.024 77.0 noncon
hsa-miR-5687 351-358 -0.45 99.0 -0.141 93.0 noncon
hsa-miR-6726-5p 727-734 -0.446 98.0 -0.024 42.0 noncon
hsa-miR-4300 727-734 -0.425 98.0 -0.023 44.0 noncon
hsa-miR-6846-5p 1647-1653 -0.425 95.0 -0.023 28.0 noncon
hsa-miR-6865-3p 162-168 -0.42 98.0 -0.368 98.0 noncon
hsa-miR-5591-5p 727-734 -0.409 97.0 -0.022 41.0 noncon
hsa-miR-6848-5p 1647-1653 -0.403 95.0 -0.022 26.0 noncon
hsa-miR-6761-5p 1724-1731 -0.402 99.0 -0.02 65.0 noncon
hsa-miR-6825-5p 455-462 -0.395 95.0 -0.021 34.0 noncon
hsa-miR-6776-3p 165-171 -0.394 99.0 -0.346 98.0 noncon
hsa-miR-548aw 234-241 -0.386 99.0 -0.338 99.0 noncon
hsa-miR-1233-5p 1472-1479 -0.384 97.0 -0.021 40.0 noncon
hsa-miR-3117-5p 598-605 -0.381 98.0 -0.021 40.0 noncon
hsa-miR-1227-3p 114-120 -0.379 97.0 -0.379 98.0 noncon
hsa-miR-448 360-367 -0.379 98.0 -0.121 89.0 con
hsa-miR-4537 925-932 -0.378 92.0 -0.02 28.0 noncon
hsa-miR-4999-5p 79-85 -0.376 96.0 -0.376 97.0 noncon
hsa-miR-6778-5p 1472-1479 -0.376 97.0 -0.02 39.0 noncon
hsa-miR-6770-5p 479-486 -0.375 98.0 -0.02 60.0 noncon
hsa-miR-4676-3p 1715-1722 -0.372 98.0 -0.02 64.0 noncon
hsa-miR-5692b 257-264 -0.37 99.0 -0.223 99.0 noncon
hsa-miR-5692c 257-264 -0.37 99.0 -0.223 99.0 noncon
hsa-miR-1825 117-123 -0.368 98.0 -0.368 98.0 noncon
hsa-miR-508-3p 1680-1687 -0.366 98.0 -0.02 42.0 noncon
hsa-miR-4754 1398-1404 -0.365 91.0 -0.02 21.0 noncon
hsa-miR-4719 387-394 -0.357 99.0 -0.114 95.0 noncon
hsa-miR-892c-3p 1715-1722 -0.356 98.0 -0.019 59.0 noncon
hsa-miR-377-3p 1343-1350 -0.356 97.0 -0.019 45.0 noncon
hsa-miR-920 727-734 -0.349 97.0 -0.019 49.0 noncon
hsa-miR-7641 1430-1437 -0.347 98.0 -0.019 67.0 noncon
hsa-miR-3613-5p 491-497 -0.347 97.0 -0.019 54.0 noncon
hsa-miR-545-3p 314-321 -0.346 99.0 -0.111 89.0 noncon
hsa-miR-541-3p 1003-1010 -0.344 97.0 -0.019 54.0 noncon
hsa-miR-4715-3p 113-119 -0.334 98.0 -0.334 99.0 noncon
hsa-miR-4795-3p 226-233 -0.333 98.0 -0.292 98.0 noncon
hsa-miR-452-5p 1715-1722 -0.329 98.0 -0.018 56.0 noncon
hsa-miR-3941 1549-1556 -0.323 98.0 -0.018 68.0 noncon
hsa-miR-3150a-3p 456-463 -0.318 96.0 -0.018 48.0 noncon
hsa-miR-6763-5p 456-463 -0.318 96.0 -0.018 47.0 noncon
hsa-miR-3936 1635-1641 -0.314 97.0 -0.017 38.0 noncon
hsa-miR-4786-5p 1661-1668 -0.312 97.0 -0.017 45.0 noncon
hsa-miR-654-5p 1003-1010 -0.312 95.0 -0.017 52.0 noncon
hsa-miR-450a-1-3p 1274-1281 -0.309 98.0 -0.017 52.0 noncon
hsa-miR-32-3p 276-283 -0.309 99.0 -0.1 97.0 noncon
hsa-miR-3617-3p 316-322 -0.306 95.0 -0.099 78.0 noncon
hsa-miR-147a 129-135 -0.303 99.0 -0.303 99.0 noncon
hsa-miR-5579-5p 1214-1221 -0.302 96.0 -0.017 55.0 noncon
hsa-miR-4329 1663-1670 -0.301 98.0 -0.017 70.0 noncon
hsa-miR-552-5p 324-331 -0.298 99.0 -0.097 97.0 noncon
hsa-miR-6794-5p 1649-1655 -0.297 91.0 -0.016 25.0 noncon
hsa-miR-4716-3p 1649-1655 -0.289 90.0 -0.016 23.0 noncon
hsa-miR-3926 802-809 -0.288 97.0 -0.016 43.0 noncon
hsa-miR-3139 1325-1331 -0.287 96.0 -0.016 43.0 noncon
hsa-miR-4529-5p 1512-1518 -0.287 92.0 -0.016 44.0 noncon
hsa-miR-5694 23-29 -0.286 98.0 -0.286 99.0 noncon
hsa-miR-450b-5p 236-242 -0.286 98.0 -0.251 98.0 noncon
hsa-miR-3921 1726-1732 -0.286 97.0 -0.015 54.0 noncon
hsa-miR-6811-5p 650-656 -0.284 95.0 -0.016 53.0 noncon
hsa-miR-1301-3p 734-741 -0.281 96.0 -0.016 47.0 noncon
hsa-miR-4328 549-556 -0.278 98.0 -0.015 63.0 noncon
hsa-miR-16-1-3p 434-441 -0.277 97.0 -0.015 56.0 noncon
hsa-miR-708-5p 1325-1331 -0.277 96.0 -0.015 43.0 noncon
hsa-miR-3911 129-135 -0.274 95.0 -0.274 96.0 noncon
hsa-miR-5047 734-741 -0.273 95.0 -0.015 48.0 noncon
hsa-miR-30d-3p 552-559 -0.27 98.0 -0.015 67.0 noncon
hsa-miR-6750-5p 419-425 -0.27 97.0 -0.021 70.0 noncon
hsa-miR-6822-5p 419-425 -0.27 97.0 -0.021 70.0 noncon
hsa-miR-1261 73-79 -0.27 95.0 -0.27 96.0 noncon
hsa-miR-30a-3p 552-559 -0.27 98.0 -0.015 67.0 noncon
hsa-miR-30e-3p 552-559 -0.27 98.0 -0.015 67.0 noncon
hsa-miR-28-5p 1325-1331 -0.266 95.0 -0.015 42.0 noncon
hsa-miR-125b-5p 1540-1546 -0.266 94.0 -0.015 45.0 noncon
hsa-miR-4423-3p 675-681 -0.265 93.0 -0.015 45.0 noncon
hsa-miR-190b 70-76 -0.264 93.0 -0.264 96.0 noncon
hsa-miR-190a-5p 70-76 -0.264 93.0 -0.264 96.0 noncon
hsa-miR-4653-5p 1726-1732 -0.264 97.0 -0.014 52.0 noncon
hsa-miR-497-3p 166-172 -0.263 98.0 -0.232 98.0 noncon
hsa-miR-34a-3p 317-323 -0.262 96.0 -0.086 88.0 noncon
hsa-miR-4633-3p 1324-1330 -0.262 95.0 -0.015 32.0 noncon
hsa-miR-888-3p 141-147 -0.262 97.0 -0.262 98.0 noncon
hsa-miR-3668 68-74 -0.259 94.0 -0.259 96.0 noncon
hsa-miR-493-5p 489-496 -0.254 97.0 -0.014 56.0 noncon