Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Glycogene class |
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Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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PAPS | + |
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→ |
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+ | PAP |
• Catalyzes C4 sulfation of GalNAc in GalNAc(β1-4)GlcNAcβ on N- and O-glycans.
• Required for biosynthesis of glycoprotein hormones lutropin and thyrotropin
ER | Cis- | Medial- | Trans- | TGN |
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CHST9/hsa-miR-1257 |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
---|---|---|---|---|---|---|---|---|
5'...AACAAAGACCAGU
CAUUCACA
...
3' CCAGUCUUGGGUA GUAAGUG A |
8mer | 74-81 | -0.446 | 99.0 | -0.446 | 99.0 | noncon | |
5'...CAGUAGGAAUGGA
CAUUCAC
U...
3' CCAGUCUUGGGUA GUAAGUG A |
7mer-m8 | 778-784 | -0.197 | 91.0 | -0.197 | 94.0 | noncon | |
5'...AUUGGCCAGUGGA
CAUUCAC
C...
3' CCAGUCUUGGGUA GUAAGUG A |
7mer-m8 | 199-205 | -0.174 | 87.0 | -0.174 | 92.0 | noncon |