Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (email@example.com), Yusen Zhou (firstname.lastname@example.org) or Ted Groth (email@example.com).
• MGAT2 catalyzes the transfer of β1,2-linked GlcNAc from UDP-GlcNAc to the terminal α1,6-linked Man in N-glycans
• The enzyme does not require the core chitobiosyl, α1-6 Fuc or peptide backbone. It is inhibited by the presence of Gaβb1-4 (i.e. β1-4 Gal-T) and bisecting β1-4GlcNAc (i.e. GnT-III/MGAT3)
• It is ubiquitously expressed