Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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UDP-GlcNAc [cyto] or UDP-Glc [cyto] or GDP-Man [cyto] | → | UDP-GlcNAc [Golgi] or UDP-Glc [Golgi] or GDP-Man [Golgi] |
• Antiporter transporting nucleotide sugars UDP-N-acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP-mannose (GDP-Man) from cytosol into Golgi, in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars).
ER | Cis- | Medial- | Trans- | TGN |
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SLC35D2/hsa-miR-5787 |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
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5'...GAUUCCCAAGGU
CCCAGCCA
...
3' UGGAGGGGCGCG GGGUCGG G |
8mer | 377-384 | -0.444 | 99.0 | -0.444 | 99.0 | noncon |