Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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UDP-GlcA [cyto] or UDP-GalNAc [cyto] or UDP-GlcA [cyto] or UDP-GalNAc [cyto] | → | UDP-GlcA [ER] or UDP-GalNAc [ER] or UDP-GlcA [Golgi] or UDP-GalNAc [Golgi] |
• UDP-GalNAc & UDP-GlcA transporter
ER | Cis- | Medial- | Trans- | TGN |
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SLC35D1/hsa-miR-1266-5p |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
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5'... UGAUAUCCAGGUGU
CCCUGAGA
...
3' UCGGGACAAGAUGUC GGGACUC C |
8mer | 326-333 | -0.275 | 96.0 | -0.252 | 97.0 | noncon | |
5'... AUUGAUUUUUCUCU
CCCUGAG
G...
3' UCGGGACAAGAUGUC GGGACUC C |
7mer-m8 | 3623-3629 | -0.142 | 87.0 | -0.032 | 71.0 | noncon | |
5'... CUAGCAUCUUCUGA
CCUGAGA
A...
3' UCGGGACAAGAUGUCG GGACUC C |
7mer-A1 | 1779-1785 | -0.122 | 83.0 | -0.027 | 69.0 | noncon | |
5'... UAUGGAAACCUGGA
CCCUGAG
U...
3' UCGGGACAAGAUGUC GGGACUC C |
7mer-m8 | 3326-3332 | -0.052 | 68.0 | -0.012 | 58.0 | noncon |