Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Pathway figs |
---|
Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
---|
UDP-GlcNAc [cyto] | → | UDP-GlcNAc [Golgi] |
• One of three UDP-GlcNAc antiporters (SLC35A3, ALC35B4, SLC35D2). It does not transport other nucleotide sugars
ER | Cis- | Medial- | Trans- | TGN |
---|---|---|---|---|
|
|
|
|
|
SLC35A3/hsa-miR-500a-5p |
---|
miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
---|---|---|---|---|---|---|---|---|
5'... GCUACCUUUCCUUC
CAUGAAAU
...
3' AGAGUGGGUCCAUCG UUCCUAA U |
8mer | 914-921 | -0.301 | 98.0 | -0.209 | 97.0 | noncon | |
5'... UAAAUUAUUUUGUA
AUUACAA
A...
3' AGAGUGGGUCCAUCGU UCCUAA U |
7mer-A1 | 272-278 | -0.164 | 93.0 | -0.164 | 95.0 | noncon | |
5'... UUUGAUAAAGGUGC
UUGUUCU
C...
3' AGAGUGGGUCCAUCGU UCCUAA U |
6mer | 587-593 | -0.09 | 85.0 | -0.09 | 90.0 | noncon |