Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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GlcN(6P) | → | Fruc(6P) |
• Glucosamine 6 phosphate deaminase removes the amine from glucosamine and produces fructose 6 phosphate in the hexosamine biosynthesis pathway.
• Allosterically activated by the accumulation of GlcNAc-6-phosphate created by GNPNAT1(GNA1).
ER | Cis- | Medial- | Trans- | TGN |
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GNPDA1/hsa-miR-1286 |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
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5'...CCCACUUAAAAUA
GUCCUGC
U...
3' UCCCGAGUAGAAC CAGGACG U |
7mer-m8 | 988-994 | -0.374 | 98.0 | -0.365 | 98.0 | noncon |