Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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H2O | + |
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→ |
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+ |
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• Alpha-galactosidase A hydrolyzes of GSLs in lysosomes.
• Sphingolipid activator protein B (SAP-B) is required for alpha galactosidase A to function in lysosomes
ER | Cis- | Medial- | Trans- | TGN |
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GLA/hsa-miR-550a-3-5p |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
---|---|---|---|---|---|---|---|---|
5'...AAAAAAAAAAGC
CAGGCACA
...
3' GAGAAUGAGGGA GUCCGUG A |
8mer | 359-366 | -0.307 | 94.0 | -0.003 | 26.0 | noncon | |
5'...CAGGUAUGGUAA
CAGGCAC
C...
3' GAGAAUGAGGGA GUCCGUG A |
7mer-m8 | 1358-1364 | -0.207 | 85.0 | -0.002 | 24.0 | noncon | |
5'...GGAUGUAUAGGC
CAGGCAC
G...
3' GAGAAUGAGGGA GUCCGUG A |
7mer-m8 | 840-846 | -0.112 | 62.0 | -0.001 | 21.0 | noncon | |
5'...CCAGGCAGGUGG
CAGGCAC
C...
3' GAGAAUGAGGGA GUCCGUG A |
7mer-m8 | 984-990 | -0.02 | 17.0 | 0.0 | 14.0 | noncon |