Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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GalNAc | → | GalNAc(1P) |
• Phosphorylates Nacetylgalactosamine to form Nacetylgalactosamine 1 phosphate. Involved in the sugar nucleotide synthesis of UDP-galactose.
• Important enzyme for salvage pathway to obtain UDP-GalNAc via Leloir pathway
ER | Cis- | Medial- | Trans- | TGN |
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GALK2/hsa-miR-4768-5p |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
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5'...AAUGUAAAAAGUCU
GAGAGAAA
...
3' UAGGUACCCUAGGU CUCUCUU A |
8mer | 18-25 | -0.415 | 98.0 | -0.415 | 98.0 | noncon |