Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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No reaction | → |
• This is an essential regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex, which includes DPM1 and DPM3.
• This protein is also part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of GlcNAc UDP-GlcNAc to phosphatidylinositol during first step of GPI biosynthesis
ER | Cis- | Medial- | Trans- | TGN |
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DPM2/hsa-miR-1299 |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
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5'...UCCCCGACUCCCAC
UUCCAGAA
...
3' AGGGAGUGUGUCUU AAGGUCU U |
8mer | 181-188 | -0.35 | 98.0 | -0.35 | 98.0 | noncon |