Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).
Pathway figs |
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Glycosylation |
Sugar Nucleotide |
Glucuronidation |
Glycan Degradation |
Pathway Map |
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+ |
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→ |
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+ | UDP |
• GlcA-transferase activity that catalyzes formation of core tetrasaccharide unit that is part of O-Xyl connection to protein core.
• Critical for HS and CS biosynthesis.
• May play minor role in the biosynthesis of HNK-1 carbohydrate epitope.
ER | Cis- | Medial- | Trans- | TGN |
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B3GAT3/hsa-miR-454-5p |
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miRNA Target | Site Type | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
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5'...AUACUGUAUAUGUC
GAUAGGG
U...
3' CGUCUCUGUUAUAA CUAUCCC A |
7mer-m8 | 314-320 | -0.261 | 92.0 | -0.001 | 23.0 | noncon |