GlycoEnzDB
The Comprehensive Glyco-enzyme Database
GlycoEnzDB
Create glycosylation pathway
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Instructions/Reference
CALR


 General Info

 About

 Related Pathway

 Related Database

 Enzyme Specificity

 Simulation Para.

 Expression Data

 Cancer Cell Line

 Transcription factor

 miRNA-GlycoEnzyme


General Information
Gene Symbol:   
CALR
Protein name:   
Calreticulin
Enzyme Class:   
CAZy Family:   
E.C. No:   
Reaction (SNFG):   

→
Reaction (IUBMB):   
No specified reaction.
About

* Calcium-binding chaperone/lectin that promotes folding, oligomeric assembly and quality control in the endoplasmic reticulum (ER)
* It binds monoglucosylated glycoproteins to aid quality control
* Acts in concert with calnexin.

Related Pathway
KEGG ORTHOLOGY:   
KEGG Pathway:   
No Record 
Reactome:   
R-HSA-1236974
Related Database
Organism:   
Homo sapiens
Uniprot:   
P27797 
NCBI GeneID:   
811
GlyMap GeneID:   
811
DNA_RefSeq:   
NM_004343.3 
Protein_RefSeq:   
NP_004334.1 
BRENDA:   
Kinetic info.
OMIM number:   
109091
GeneCards database:   
CALR
Enzyme Specificity
Glycan Type:  
     
Compartment:  
     
Substrate:  
     (-CHAR)
Product:  
     (-CHAR)
Simulation Parameters
Mechaelis-Menten parameters (suggested)
Vm:       (pmol/cell • hr)       Km:       (pM)
Relative conc of enzymes in compartment.(sum will be normalized to 1)
ER Cis- Medial- Trans- TGN










Expression Data in Tissues
No expression data available.
Cancer Cell Line Encyclopedia {ref. 13} Source from Cancer Cell Line Encyclopedia database
Kidney Lung Breast Prostate Large intestine Ovary HL60 haematopoietic and lymphoid tissue Skin Central nervous system 786O A498 ACHN CAKI1 UO31 A549 EKVX HOP62 HOP92 NCIH226 NCIH23 NCIH322 NCIH460 NCIH522 SHP77 BT549 HS578T MCF7 MDAMB231 MDAMB468 T47D DU145 PC3 HCT116 HCT15 HT29 KM12 SW620 OVCAR4 OVCAR8 IGROV1 SKOV3 HL60 K562 RPMI8226 LOXIMVI MALME3M RPMI7951 SKMEL28 SKMEL5 UACC257 UACC62 SF268 SF295 SF539 SNB75 3400 3300 3200 3100 3000 2900 2800 2700 2600 2500 2400 2300 2200 2100 2000 1900 1800 1700 1600 1500 1400 1300 1200 1100 1000 900 800 700 600 500 400 300 200 100 0 Transcripts per million (TPM)
Transcription factor {ref. 10}
No high degree of confidence data