GlyClass

GlycoEnzDB
Comprehensive glycoEnzyme database and dynamic pathway generation

Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (neel@buffalo.edu), Yusen Zhou (yusenzho@buffalo.edu) or Ted Groth (tgroth@buffalo.edu).

GlycoEnzDB
Create glycosylation pathway
Custom database generation
Instructions/Reference
 
Pathway Map
OGA



General Information
Gene Symbol:   
OGA
Protein name:   
Protein O-GlcNAcase
Enzyme Class:   
Glycosidase
CAZy Family:   
GH84
E.C. No:   
3.2.1.169
Organs:   
Reaction (SNFG):   
OGA OGA
H2O +
→
+
H2O +
→
+
Reaction (IUBMB):   
No specified reaction.
About
no comments
Related Pathway
KEGG ORTHOLOGY:   
K15719
KEGG Pathway:   
No Record 
Reactome:   
No Record
Related Database
Organism:   
Homo sapiens
Uniprot:   
O60502 
NCBI GeneID:   
10724
GlyMap GeneID:   
10724
DNA aRefSeq:   
NM_001142434.1 
Protein RefSeq:   
NP_001135906.1 
BRENDA:   
Kinetic info.
OMIM number:   
604039
GeneCards database:   
OGA
Enzyme Specificity
Glycan Type:  
     O-linked (other)
Compartment:  
     
Substrate:  
     GlcNAc(b1-r):Ser or GlcNAc(b1-r):Thr
Product:  
     Ser or Thr
Simulation Parameters
Mechaelis-Menten parameters (suggested)
VM:       (pmol/cell • hr)       KM:       (pM)
Relative conc of enzymes in compartment.(sum will be normalized to 1)
ER Cis- Medial- Trans- TGN










Expression Data in Tissue {ref. 5} Source from NCBI gene database
adrenal appendix bone marrow brain colon duodenum endometrium esophagus fat gall bladder heart kidney liver lung lymph node ovary pancreas placenta prostate salivary gland skin small intestine spleen stomach testis thyroid urinary bladder 50 40 30 20 10 0 RPKM
Expression Data in Cells
No expression data available.
Transcription factor {ref. 10}
No high degree of confidence data