Description: The GlycoEnzDB is a manually curated glycoEnzyme database, primarily focused on humans. It covers 390 enzymes across 28 pathway maps. Facilities are also available to create custom glycosylation reaction pathways using experimental data in SBML format and for pathway simulation
Contacts: Sriram Neelamegham (firstname.lastname@example.org), Yusen Zhou (email@example.com) or Ted Groth (firstname.lastname@example.org).
• This enzyme is often called GM2/GD2 synthase at it produces GM2, GD2 and also asialo GA2. These complex gangliosides were all deleted in the B4GALNT1 knockout mice.
• Levels of these genes and related structures (e.g. GD2) may be upregulated during malignancy.