GlycoEnzDB
The Comprehensive Glyco-enzyme Database
GlycoEnzDB
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Instructions/Reference
POGLUT2


 General Info

 About

 Related Pathway

 Related Database

 Enzyme Specificity

 Simulation Para.

 Expression Data

 Cancer Cell Line

 Transcription factor

 miRNA-GlycoEnzyme


General Information
Gene Symbol:   
POGLUT2
Protein name:   
Protein O-glucosyltransferase 2
Enzyme Class:   
Glycosyltransferase
CAZy Family:   
GT90
E.C. No:   
2.4.1.*
Reaction (SNFG):   
+
→
+ UDP
Reaction (IUBMB):   
No specified reaction.
About

* Protein GlcTs POGLUT2 and POGLUT3 catalyzes O-Glc biosynthesis on serine residue between 3rd and 4th Cys in EGF domain of selected proteins: NOTCH1 and NOTCH3
* Such glycosylation occurs at the consensus sequence peptide C-X-N-T-X-G-S-F-X-C

Related Pathway
KEGG ORTHOLOGY:   
KEGG Pathway:   
No Record 
Reactome:   
Related Database
Organism:   
Homo sapiens
Uniprot:   
Q6UW63 
NCBI GeneID:   
79070
GlyMap GeneID:   
79070
DNA_RefSeq:   
NM_001318732.1 
Protein_RefSeq:   
NP_001305661.1 
BRENDA:   
Kinetic info.
OMIM number:   
611613
GeneCards database:   
POGLUT2
Enzyme Specificity
Glycan Type:  
     O_linked (not mucin type)
Compartment:  
     
Substrate:  
     Ser
Product:  
     Glc(a1-?)Ser
Simulation Parameters
Mechaelis-Menten parameters (suggested)
Vm:       (pmol/cell • hr)       Km:       (pM)
Relative conc of enzymes in compartment.(sum will be normalized to 1)
ER Cis- Medial- Trans- TGN










Expression Data in Tissues
No expression data available.
Expression Data in Cells
No expression data available.
Transcription factor {ref. 10}
No high degree of confidence data