GlycoEnzDB
The Comprehensive Glyco-enzyme Database
GlycoEnzDB
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Instructions/Reference
PIGZ



General Information
Gene Symbol:   
PIGZ
Protein name:   
GPI mannosyltransferase 4
Enzyme Class:   
Glycosyltransferase
CAZy Family:   
E.C. No:   
Reaction (SNFG):   

[6EtNP]Man(a1-2)[6EtNP]Man(a1-6)[2EtNP]Man(a1-4)GlcN(a1-6)(ancyl)PI Man(a1-2)[6EtNP]Man(a1-2)[6EtNP]Man(a1-6)[2EtNP]Man(a1-4)GlcN(a1-6)(ancyl)PI
Reaction (IUBMB):   
No specified reaction.

About

* This transfers the fourth Man from Dol-P-Man during GPI-anchored protein biosynthesis


Related Pathway
KEGG ORTHOLOGY:   
KEGG Pathway:   
Reactome:   

Related Database
Organism:   
Homo sapiens
Uniprot:   
NCBI GeneID:   
GlyMap GeneID:   
DNA_RefSeq:   
Protein_RefSeq:   
BRENDA:   
OMIM number:   
GeneCards database:   

Enzyme Specificity
Glycan Type:  
     GPI
Compartment:  
     ER
Substrate:  
     [6EtNP]Man(a1-2)[6EtNP]Man(a1-6)[2EtNP]Man(a1-4)GlcN(a1-6)(ancyl)PI(-CHAR)
Product:  
     Man(a1-2)[6EtNP]Man(a1-2)[6EtNP]Man(a1-6)[2EtNP]Man(a1-4)GlcN(a1-6)(ancyl)PI(-CHAR)

Simulation Parameters
Mechaelis-Menten parameters (suggested)
Vm:       (pmol/cell • hr)       Km:       (pM)
Relative conc of enzymes in compartment.(sum will be normalized to 1)
ER Cis- Medial- Trans- TGN











Expression Data {ref. 5} Source from NCBI gene database
adrenal appendix bone marrow brain colon duodenum endometrium esophagus fat gall bladder heart kidney liver lung lymph node ovary pancreas placenta prostate salivary gland skin small intestine spleen stomach testis thyroid urinary bladder 8 6 4 2 0 RPKM
Expression data are collected from NCBI gene database

Expression Data in Cells
No expression data available.
Transcription factor {ref. 10}
No high degree of confidence data