GlycoEnzDB

General Information

Gene Symbol:

PIGY

Protein name:

Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y

Enzyme Class:

Glycosyltransferase

CAZy Family:

E.C. No:

Reaction (SNFG):

No reaction

→

Reaction (IUBMB):

No specified reaction.

About

* GPI-GnT: GlcNAcT activity that is necessary to form the core glycan structure on GPI-anchored proteins
* Subunit PIGA has catalytic activity, while PIGC, PIGH, PIGQ, PIGP and PIGY have other essential functions
* DPM2 is regulatory and it functions to enhance GPI-GnT activity

Related Pathway

KEGG ORTHOLOGY:

K11001

KEGG Pathway:

ko00563 ko01100

Reactome:

R-HSA-162710

Related Database

Organism:

Homo sapiens

Uniprot:

Q3MUY2

NCBI GeneID:

84992

GlyMap GeneID:

84992

DNA_RefSeq:

NM_001042616.2

Protein_RefSeq:

NP_001036081.1

BRENDA:

Kinetic info.

OMIM number:

610662

GeneCards database:

PIGY

Enzyme Specificity

Glycan Type:

GPI

Compartment:

ER

Substrate:

No reaction(-CHAR)

Product:

(-CHAR)

Simulation Parameters

Mechaelis-Menten parameters (suggested)
Vm: (pmol/cell • hr) Km: (pM)
Relative conc of enzymes in compartment.(sum will be normalized to 1)

ER	Cis-	Medial-	Trans-	TGN

Expression Data {ref. 5} Source from NCBI gene database

Expression data are collected from NCBI gene database

Expression Data in Cells

No expression data available.

Transcription factor {ref. 10}

No high degree of confidence data