GlycoEnzDB
The Comprehensive Glyco-enzyme Database
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R(-CHAR).jpg)
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GlcNAc(b1-0)R(-CHAR).jpg)
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R(-CHAR).jpg)
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GalNAc(b1-0)R(-CHAR).jpg)
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+ | UDP |
* Produces type 1 chain linkage in glycolipids and core-3 O-glycans, but not N-linked glycoproteins.
* May be an important enzyme forming CA19-9 in colon cancer. Beyond serving as a biomarker, CA19-9 also promotes pancreatitis and pancreatic cancer (in mice).
* B3GalT5 efficiently transfers Gal to the GlcNAc of the glycolipid Lc3Cer and to the terminal GalNAc residue of the globoside Gb4.
* It may thus contribute to the formation of CA 19-9, SSEA-3 and elongated core-3 O-glycans.
* Expression is restricted to the colorectum, small intestine, stomach, and pancreas.
| ER | Cis- | Medial- | Trans- | TGN |
|---|---|---|---|---|
| miRNA Name | Pos. | Context Score | Frac. | Wt. Context | Frac. | Conserved | Quality |
|---|---|---|---|---|---|---|---|
| hsa-miR-151a-5p | 11594-11601 | -0.559 | 98.0 | -0.559 | 99.0 | noncon | |
| hsa-miR-151b | 11594-11601 | -0.559 | 98.0 | -0.559 | 99.0 | noncon | |
| hsa-miR-425-3p | 11151-11158 | -0.482 | 98.0 | -0.482 | 98.0 | noncon | |
| hsa-miR-6506-3p | 11536-11543 | -0.453 | 96.0 | -0.453 | 97.0 | noncon | |
| hsa-miR-187-3p | 10927-10934 | -0.447 | 95.0 | -0.447 | 97.0 | noncon | |
| hsa-miR-4763-5p | 11452-11459 | -0.409 | 95.0 | -0.409 | 97.0 | noncon | |
| hsa-miR-6775-5p | 4275-4281 | -0.398 | 95.0 | -0.398 | 96.0 | noncon | |
| hsa-miR-4266 | 5416-5423 | -0.393 | 97.0 | -0.393 | 98.0 | noncon | |
| hsa-miR-4266 | 1281-1287 | -0.392 | 97.0 | -0.392 | 98.0 | noncon | |
| hsa-miR-4706 | 659-666 | -0.38 | 94.0 | -0.38 | 95.0 | noncon | |
| hsa-miR-4749-5p | 659-666 | -0.37 | 94.0 | -0.37 | 95.0 | noncon | |
| hsa-miR-5091 | 7319-7325 | -0.368 | 92.0 | -0.368 | 95.0 | noncon | |
| hsa-miR-7108-3p | 75-82 | -0.36 | 93.0 | -0.36 | 95.0 | noncon | |
| hsa-miR-6749-5p | 178-184 | -0.352 | 93.0 | -0.352 | 94.0 | noncon | |
| hsa-miR-5090 | 4275-4281 | -0.351 | 92.0 | -0.351 | 94.0 | noncon | |
| hsa-miR-6769b-3p | 5281-5288 | -0.335 | 97.0 | -0.335 | 98.0 | noncon | |
| hsa-miR-6726-5p | 511-518 | -0.333 | 95.0 | -0.333 | 96.0 | noncon | |
| hsa-miR-5591-5p | 511-518 | -0.32 | 95.0 | -0.32 | 96.0 | noncon | |
| hsa-miR-4723-3p | 5281-5288 | -0.311 | 96.0 | -0.311 | 97.0 | noncon | |
| hsa-miR-6812-5p | 841-848 | -0.305 | 94.0 | -0.305 | 95.0 | noncon | |
| hsa-miR-4300 | 511-518 | -0.296 | 94.0 | -0.296 | 95.0 | noncon | |
| hsa-miR-4498 | 3613-3620 | -0.292 | 92.0 | -0.292 | 94.0 | noncon | |
| hsa-miR-4802-5p | 10617-10623 | -0.29 | 96.0 | -0.29 | 97.0 | noncon | |
| hsa-miR-505-3p.1 | 11295-11302 | -0.289 | 91.0 | -0.289 | 94.0 | noncon | |
| hsa-miR-5001-5p | 8651-8658 | -0.289 | 92.0 | -0.289 | 94.0 | noncon | |
| hsa-miR-4777-3p | 7727-7734 | -0.289 | 93.0 | -0.289 | 95.0 | noncon | |
| hsa-miR-6819-5p | 841-848 | -0.287 | 93.0 | -0.287 | 95.0 | noncon | |
| hsa-miR-5001-5p | 3613-3620 | -0.286 | 92.0 | -0.286 | 93.0 | noncon | |
| hsa-miR-191-3p | 10638-10645 | -0.281 | 93.0 | -0.281 | 95.0 | noncon | |
| hsa-miR-6737-5p | 841-848 | -0.279 | 93.0 | -0.279 | 94.0 | noncon | |
| hsa-miR-4498 | 8651-8658 | -0.279 | 91.0 | -0.279 | 93.0 | noncon | |
| hsa-miR-660-5p | 11029-11036 | -0.275 | 95.0 | -0.275 | 97.0 | noncon | |
| hsa-miR-323a-5p | 6834-6841 | -0.274 | 94.0 | -0.274 | 95.0 | noncon | |
| hsa-miR-1915-5p | 296-303 | -0.274 | 91.0 | -0.274 | 94.0 | noncon | |
| hsa-miR-4471 | 149-156 | -0.271 | 93.0 | -0.271 | 95.0 | noncon | |
| hsa-miR-4476 | 5947-5954 | -0.27 | 97.0 | -0.27 | 98.0 | noncon | |
| hsa-miR-6791-5p | 1866-1872 | -0.267 | 94.0 | -0.267 | 96.0 | noncon | |
| hsa-miR-149-3p | 7030-7036 | -0.266 | 94.0 | -0.266 | 95.0 | noncon | |
| hsa-miR-324-5p | 2241-2248 | -0.263 | 90.0 | -0.263 | 93.0 | noncon | |
| hsa-miR-4663 | 5125-5132 | -0.26 | 96.0 | -0.26 | 97.0 | noncon | |
| hsa-miR-920 | 511-518 | -0.26 | 95.0 | -0.26 | 96.0 | noncon | |
| hsa-miR-1200 | 1404-1411 | -0.257 | 96.0 | -0.257 | 97.0 | noncon | |
| hsa-miR-6828-3p | 10548-10555 | -0.256 | 95.0 | -0.256 | 96.0 | noncon | |
| hsa-miR-214-3p | 10320-10326 | -0.255 | 96.0 | -0.255 | 97.0 | noncon | |
| hsa-miR-3606-5p | 10849-10855 | -0.255 | 93.0 | -0.255 | 96.0 | noncon | |
| hsa-miR-6514-3p | 293-300 | -0.255 | 97.0 | -0.255 | 98.0 | noncon | |
| hsa-miR-149-3p | 1964-1971 | -0.254 | 93.0 | -0.254 | 94.0 | noncon | |
| hsa-miR-4728-5p | 7030-7036 | -0.253 | 93.0 | -0.253 | 94.0 | noncon | |
| hsa-miR-1324 | 11633-11639 | -0.25 | 96.0 | -0.25 | 97.0 | noncon | |
| hsa-miR-1199-5p | 733-740 | -0.25 | 94.0 | -0.25 | 96.0 | noncon |